Dual Antiplatelet Therapy for Heart Disease

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Dual antiplatelet therapy for heart disease.

Dual Antiplatelet Therapy for Heart Disease Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2014 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/CIRCULATIONAHA.113.004305 2014;129:e506-e508 Circulation. http://circ.ahajournals.org/content/129/21/e506 World Wide Web a...

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Antiplatelet therapy for ischemic heart disease.

Rupture or injury of an atherosclerotic coronary arterial plaque — as occurs spontaneously in patients with an acute coronary syndrome or as the result of a percutaneous coronary intervention — serves as a nidus for platelet aggregation and thrombus formation, which, in turn, may cause myocardial infarction or death. Activation of the platelet-surface glycoprotein IIb/IIIa receptor is the final...

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Dual antiplatelet therapy for secondary prevention of coronary artery disease

Dual antiplatelet therapy (DAPT) combining aspirin and a P2Y12 receptor inhibitor has been consistently shown to reduce recurrent major adverse cardiovascular events (MACE) in patients with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI) for stable coronary artery disease (CAD) compared with aspirin monotherapy, but at the expense of an increased risk of maj...

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An update of dual antiplatelet therapy

Since platelet activation and aggregation play a major role in thrombus formation in lumen of coronary arteries, they constitute a main target in treatment of stable ischemic heart disease and acute coronary syndromes. Antiplatelet therapy should be commenced as early as possible within the current indications in order to reduce the risk of both acute ischemic complications and recurrent athero...

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[Comment about patients with dual antiplatelet therapy].

We have read with great interest the article by Dr. Bassas et al regarding the use of antiplatelet and anticoagulant treatment in dermatological surgery. We would like to congratulate the authors on their excellent and exhaustive review.1 We agree with their conclusion: there is no scientific evidence supporting the withdrawal of antiplatelet therapy in dermatological surgery settings, and it i...

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ژورنال

عنوان ژورنال: Circulation

سال: 2014

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.113.004305